An important aspect is the host selectivity and substrate specificity of these systems
It is notable that obesity and depression often occur together, and both conditions show dysregulation in the default mode network (DMN) activity
16 17 18 Newly emerging indications for GLP-1 medicationsincluding heart disease, metabolic liver disease, peripheral artery disease, Alzheimers/dementia risk, and even alcohol and substance use disorders, as highlighted in a 2025 study in JAMA 19 suggest these drugs may soon play a much broader role in medicine than just treating diabetes or obesity
VITAMINS Vitamins are bioregolators of great importance as they preside, together with the hormones, to carry out all the physiological processes both directly and indirectly through enzymatic mechanisms
The leaves also, besides the nutritious value, contain a large variety of secondary metabolites that exert anti-microbial, antioxidant, growth, and immune enhancing activities making the plant a potential alternative dietary supplement to livestock and poultry for organic meat and egg production, which has received a great public demand in recent years [32]
