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Patients received pre-prepared investigational product from Eli Lilly

Especially in the prodromal stage of the diseases, nutritional ketosis might delay start of symptoms

Exclusion criteria included intake of carnitine, history of seizures, brain metastasis, nausea more than grade 1, and severely compromised renal, liver, or respiratory function

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These findings, along with indications of safety and potential benefits for PAD outcomes, suggest that GLP-1RAs could be considered a preferred therapy over other anti-diabetic medications for patients with concurrent T2DM and PAD [79]