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We were unable to robustly increase bulk acetyl-CoA or consistently increase histone acetylation on addition of acetate in shTMLHE cells (Extended Data Fig

doi: 10.3390/compounds3010005 89 ArrudaTRJuniorBRDCMarquesCSBernardesPCMagalhesCGPinheiroPF

Protecting Against Liver Damage Glutathione deficiency spells trouble for the liver, increasing the risk of cell damage

Given the proposal to discontinue the low wage index hospital policy under the IPPS in the FY 2026 IPPS/LTCH PPS proposed rule and the absence of the timing issues which compelled us to continue the low wage index hospital policy under the OPPS for CY 2025, we stated in the CY 2026 OPPS/ASC proposed rule that we think it is now appropriate to return to our longstanding policy of using the IPPS wage index as the source of an adjustment factor for the OPPS