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W.SedrakyanS.NavarreteG.et al (2015)

Glutathione production unfortunately decreases with age

In 2018, Franciss team reported that using a sensory reconstitution study they had determined that it is a mixture of monoterpenes and lactones that gives rise to this stone-fruit flavour

They reduce A1c by 1% to 1.5%, whereas products like the DPP-4s and SGLT2s at the high end can get up to 1% reduction

The decreased effect of exendin-4 is not specific to the NOD mouse colony at the Department of Pathology, as this was also observed in other NOD mouse colonies (Supplementary figure 1a, 1b), and the effect does not appear to be dominant, as F1 offspring of a C57BL/6xNOD cross do exhibit a response to injection of exendin-4 (Fig