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The presence of targeting ligands resulted in two-fold higher uptake of nanocarriers in the control healthy (2.09 ng/g protein) and PD organoids (1.85 ng/g protein) compared to uptake of the non-targeted nanocarriers in the control (1.01 ng/g protein) and PD (0.92 ng/g protein) organoids (Fig

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The MTHFD2 encoded enzyme is an NAD + /NADP + -dependent enzyme that possesses 5,10-methylene-THF dehydrogenase and 5,10-methenyl-THF cyclohydrolase activities

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