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The drug's half-life is approximately 5 days, meaning it takes 5 days for half the injected dose to clear your system (Urva et al., Clinical Pharmacokinetics 2022)

Lilly Launches Trulicity in the US First Ever Ready-to-Use Once-Weekly GLP-1 Receptor Agonist Twitter summary: @LillyDiabetes launches Trulicity in the US first ready-to-use once-weekly GLP-1, available w/savings program for commercially insured On November 10, Eli Lilly and company announced that Trulicity (dulaglutide) is now available in the US, making it the first ready-to-use once weekly GLP-1 receptor agonist to reach the market (no mixing required)

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Most versions require a prescription, except for oral forms