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Plotting the degree of reduction of the respective sensor variants against the redox potential of the ambient LA/DHLA buffer allowed to deduce E values of 237.7 2 mV for roGFP2-iL (Figure 4A) and 243.2 5 mV for GRX1-roGFP2-iL (Figure 4B)

doi: 10.1172/JCI174910 145 SicardJ

They significantly influence obesity by modulating food intake, lipid synthesis and catabolism, as well as the differentiation and maturation of adipocytes