This is among the highest weight reductions yet seen in a phase 3a programme for a GLP-1 combination therapy
[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Rasic D., Zenko Sever A., Rasic F., Strbe S., Rasic Z., Djuzel A., Duplancic B., Boban Blagaic A., Skrtic A., Seiwerth S., et al
Method Literature search strategy Google Scholar and PubMed were searched on various dates between December 2016 and March 2017, ending on 15th March 2017 using the following terms, and variants thereof, and all articles discovered were considered for inclusion: (paracetamol OR acetaminophen hepatotoxicity) AND genetic differences/polymorphisms OR children/neonates/young people/paediatric OR older people/elderly/geriatric OR nutritional state/malnutrition OR body weight/low body weight OR alcohol/alcohol-dependence OR drug interactions/potentiation OR liver disease/chronic liver disease/liver failure
Together this aids in weight management, while maintaining lean muscle gains
This weight loss is attributed to its effects on appetite and satiety