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Moreover, interindividual heterogeneity driven by genetic variation (particularly VDR polymorphisms), metabolic comorbidities, and chronic low-grade inflammation further confounds the predictability of therapeutic efficacy

After consumption of 5.28 and 1.06 g Pycnogenol by one volunteer, conjugates of ferulic acid and taxifolin were found in urine samples 23 h after intake

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The two are related, but not the same