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A 2025 study evaluating patients with diabetes found that those using GLP-1 drugs may be at a lower risk of developing Alzheimers disease and other types of dementia

Consider whether accepting higher stable weight might be more sustainable than cycling through loss and regain

Some studies suggest that successful weight loss may improve mental health outcomes in many patients, potentially offsetting any direct medication effects

Brand-name drugs typically cost more than generics

Table 1: Initial use restrictions for Wegovy by commercial plans Source: Clarivate Fingertip Restrictions and payers respective prior authorization documents In addition to a relatively light hand in restricting access, Aetna, Cigna, and Anthem list Wegovy on Tier 2 of their commercial and employer formularies, reflecting widespread coverage for the drug (Fingertip Analytics, accessed February 2024)