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IOM, 1998)
Sleep improvements are typically the first effect patients notice, followed by better energy and overall recovery as the cycle progresses
Adding cagrilintide theoretically provides additional satiety signaling through the amylin pathway, potentially pushing total weight loss beyond 30%
These approaches are broadly consistent with guidance used for managing fatigue associated with other GLP-1 receptor agonists, as reflected in NHS and NICE resources for weight management pharmacotherapy (including NICE TA875 on semaglutide for weight management)
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