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Research shows it blocks UV-induced erythema without making skin more susceptible to sun damage

May help support the integrity of tendons, ligaments, and joints, making it a popular option for individuals dealing with physical stress or repetitive strain

New Phytol 224:15691584 Maynard D, Kumar V, Spro J, Dietz K-J (2020) 12-Oxophytodienoic acid reductase 3 (OPR3) functions as NADPH-dependent , -ketoalkene reductase in detoxification and monodehydroascorbate reductase in redox homeostasis

Each component is associated in published preclinical literature with distinct mechanistic pathways, and the blend format allows laboratories to prepare all four under matched conditions for parallel single-agent and combined-arm experiments

This is explored in research on the effects of NNMT knockdown in fat and liver tissue