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This is a mechanistic inference, not a human finding, but it illustrates why unregulated IGF-1R agonism is not treated casually in the scientific literature

doi: 10.1167/iovs.16-19988 90

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It has been studied for its possible therapeutic benefits, such as treatment for insomnia, stress relief, and as an adjunct therapy for various conditions that are influenced by stress or disrupted sleep patterns