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See CMS's Medicare Coverage Center Please note also that Clinical Policy Bulletins (CPBs) are regularly updated and are therefore subject to change

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In rats, R -lipoic acid was more effective than S -lipoic acid in enhancing insulin-stimulated glucose transport and metabolism in skeletal muscle (110), and R -lipoic acid was more effective than R,S -lipoic acid and S -lipoic acid in preventing cataracts (111)

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