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For the 9 mg target, doses increased in steps at 2 mg, 4 mg, and 6 mg, with increases every four weeks until reaching 9 mg

In its Phase 2 obesity trial it produced the largest average body-weight reductions yet reported for a once-weekly agent but every gram of that effect was built on a slow, deliberate dose-escalation schedule

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And the maintenance phase, where you settle at your optimal dose, covers the remaining weeks

Doctors are describing the results as very solid and exciting, with some calling the weight loss and A1C reduction excellent. To the surprise of many, weekly retatrutide shots resulted in a decrease in body fat and blood sugar