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Fatigue is real but sits well below the gastrointestinal reactions that dominate the profile

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Given these associations, rigorous monitoring and treatment of comorbidities, particularly cardiovascular risk factors, could improve MS outcomes 60,64

While Semaglutide targets only GLP-1 receptors and Tirzepatide hits both GLP-1 and GIP receptors, Retatrutide adds glucagon receptor activation to the mix