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A recent clinical trial evaluated empagliflozin as an add-on to citalopram in 90 patients with moderate to severe depression, showing significant reductions in the Hamilton Depression Rating Scale and depressive symptoms at weeks 4 and 8 [193]

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[425] Reliability of the measure was assessed with the Cronbach alpha score [426] to determine whether the survey questions reliably measure the same underlying characteristic, that is, patients' assessment of the clarity and applicability of recovery instruction