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Checkpoint blockade of MDSCs in combination with existing immunotherapies has emerged as a potential approach to enhance anti-tumor immunity [9]

This function is essential for reducing inflammation and supporting long-term health

SinghRPBhaiyyaRThakurRNiharikaJSinghCLatousakisDet al

A sustained activation of Ca 2+ -permeable channels due to an impaired glutamate uptake by astrocytes (Mori et al., 2004) leads to a pathological increase in intracellular Ca 2+ ([Ca 2+ ] i ) and overexcites the cells which in turn release harmful substances, such as reactive oxygen species (ROS