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Comparable to therapy with GLP-1RA, a stepwise dose escalation starting with a low starting dose was associated with a lower rate of gastrointestinal side effects and better tolerability of tirzepatide (67)

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A co-occurrence network analysis revealed three clusters of frequently co-mentioned symptoms

Researchers working with subjects outside this profile should account for several population-specific considerations that affect how the retatrutide escalation schedule performs and how outcomes should be interpreted

The Weight Watchers difference: At 6 months, our Med+ members on the GLP-1 Success Program lost 27 lbs, on average.^ ^Based on a 6-month clinical trial (n=180) of individuals who were enrolled between FebruaryApril 2024, with overweight or obesity taking semaglutide or tirzepatide for weight loss and related outcomes through the WW Clinic Program and participating in the GLP-1 companion nutrition program