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TB-500s larger molecular weight suggests oral bioavailability is limited, making subcutaneous or intramuscular administration standard for research purposes

Sciatica refers to a pattern of pain that radiates along the sciatic nerve's pathway

LPS administration caused characteristic morphological changes in lung sections, including severe immune cell infiltration, interstitial edema, alveolar wall thickening, and hemorrhage, indicative of successful ALI induction

Intranasal administration is being explored for direct central nervous system delivery via olfactory and trigeminal nerve pathways, bypassing the blood-brain barrier and hepatic metabolism entirely

Research by Khorram et al