In dermatological contexts, the most clinically relevant gene targets include: COL1A1 and COL3A1 upregulation increases procollagen type I and III synthesis, directly counteracting age-related collagen depletion
Examples of FDA-approved peptides: Semaglutide (Ozempic, Wegovy): Approved for: Type 2 diabetes (Ozempic), obesity (Wegovy) Legal status: Prescription required, completely legal Schedule: Not a controlled substance Availability: Through licensed pharmacies with valid prescription Tirzepatide (Mounjaro, Zepbound): Approved for: Type 2 diabetes (Mounjaro), obesity (Zepbound) Legal status: Prescription required, completely legal Recent: Approved 2022-2023 Tesamorelin (Egrifta): Approved for: HIV-associated lipodystrophy (belly fat) Legal status: Prescription required, completely legal Sermorelin, CJC-1295 (with DAC - as Tesamorelin precursor): Some formulations approved for specific conditions Generally require prescription through compounding pharmacies PT-141 (Bremelanotide/Vyleesi): Approved for: Female sexual dysfunction Legal status: Prescription required, completely legal Key point: If a peptide is FDA-approved and you have a legitimate prescription, it's 100% legal
Zhang, Y., Chopp, M., Meng, Y., Zhang, Z
This unusual bell-shaped dose response curve suggests the peptide operates through mechanisms that remain effective even at very low concentrations
Your provider will choose the best form for you
