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Prior GHK-Cu studies showed it improves cognitive function in aged animals and counteracts oxidative stress relevant to AD pathogenesis

So S, Yamaguchi W, Murabayashi N, Miyano N, Tawara F, Kanayama N

Unlike its cyclic counterpart Melanotan II, MT-1 retains a linear backbone analogous to the 13-amino-acid natural -MSH sequence, differing primarily in a norleucine substitution at position 4 and a D-phenylalanine at position 7 (Nle-D-Phe--MSH), which confer receptor selectivity and enhanced metabolic stability

Researchers must weigh whether the brain delivery benefits outweigh the potential loss of peripheral glucagon signaling

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