B12 is involved in the key metabolic process called "One Carbon Metabolism" though, and that process can be linked to a great many critical bodily functions, including detoxification among others
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Nutr Clin Pract 33(3):419425
Additionally, patients with inflammatory bowel disease, severe gastroesophageal reflux disease, or other significant gastrointestinal disorders should be monitored closely if treatment is initiated, as the gastrointestinal effects of semaglutide may worsen their underlying condition
Each component peptide has a well-documented mechanism of action in preclinical research, and the combination targets complementary pathways in tissue repair, inflammation reduction, and collagen production