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(2023) found that GLP-1 receptor agonists reduced the risk of lower limb amputation by 43% compared to sulfonylureas (HR: 0.57, 95% CI: 0.390.84), with the greatest risk reduction observed in long-term users (HR: 0.44, 95% CI: 0.270.72).(26) However, GLP-1 receptor agonists did not significantly impact diabetic foot ulcer incidence (HR: 1.08, 95% CI: 0.871.35)

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Ozempic, also called semaglutide, may be the most well-known, but five other GLP-1s in an injectable form are used to treat diabetes

Persistent nausea that interferes with hydration, nutrition, or daily function should be discussed with a healthcare professional rather than assumed to be a normal adjustment symptom

"After months of preparation, we are proud to introduce our new California Gold Nutrition supplements specifically formulated to mitigate the adverse effects of GLP-1 therapy," said Emun Zabihi, CEO of iHerb