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Farxiga/Forxiga (dapagliflozin) Disease area(s): Metabolic diseases Manufacturer(s): AstraZeneca 2024 Sales (USD): $7.72 billion Why it sold so well: In 2024, AstraZenecas Farxiga achieved robust sales growth, with revenues increasing by 21% year-over-year to $1.9 billion in the fourth quarter alone and by 28% compared to 2023, making it the companys top seller in 2024