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This suggests that the higher rates of glucuronidation associated with this UGT1 polymorphism protect against paracetamol hepatotoxicity by decreasing the fractional proportion of paracetamol available for oxidation

Xie Y, Hou W, Song X, Yu Y, Huang J, Sun X

nevertheless, as these confounding factors underlie all groups, it is unlikely that these factors affect the conclusion

Specifically, NAC exponentially increases the production of specialized detoxification enzymes known as Glutathione S-transferases (GSTs)