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KPV inhibits NF-kB, a transcription factor that serves as the central regulator of multiple inflammatory gene programs

As discussed ( earlier, to the extent the data shows that there would be more than a limited impact on the relative weights initially, which we do not believe will be the case, we intend to provide an opportunity for additional public input and will continue to provide impact analyses of changes in the MS-DRG relative weights in the annual IPPS rulemaking

Genetic toxicology testing returned negative results across multiple assays

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