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5 This blunted response is possibly caused by the downregulation of GIP receptors (GIPR) by the high level of circulating glucose

Semaglutide GLP-1 injections operate by replicating the actions of a hormone known as glucagon-like peptide-1, or GLP-1, which has a specific influence on brain regions responsible for appetite and food consumption regulation

The exact mechanisms are not fully understood but may involve reducing appetite, improving insulin signaling, and potentially influencing gut microbiota

Watch for any reaction: redness lasting more than 30 minutes, itching, burning, breakouts in treated areas, or increased skin sensitivity to other products or environmental factors